Field cores from typical cracking locations were tested by the semi-circular bending test and the digital image correlation method to evaluate the anti-fatigue performance of different asphalt pavements. Test results were analyzed by different fatigue models. Causes of fatigue cracking for different pavement sections were determined by extraction and sieving test results. It is found that the ranking (from high to low) in terms of the anti-fatigue performance for field cores is the crumb rubber modified asphalt mixture, densegraded modified asphalt mixture, continuous graded asphalt treated base, gap-graded stone asphalt concrete, and half open-graded asphalt macadam. Compared with the half opengraded asphalt macadam, the fatigue life of the crumb rubber modified asphalt mixture improves by 2. 0 to 3. 8 times. Fatigue lives of different mixtures and distress ratios of actual pavements can be accurately predicted by the dissipated energy density ratio. Causes of fatigue cracking vary with mixture types.