CeO2,MnOx and ZnO were used as supports of Cu-based catalysts respectively in this study.The influences of these supports on the catalyst for CO oxidation in H2-rich gases were investigated.The catalysts were characterized by XRD(X-ray diffraction),BET(BET surface area),TPD(Temperature-programmed desorption) and TPR(Temperature-programmed reduction) methods.The results indicate that CuO/CeO2 catalyst has higher catalytic activity,for CO oxidation than CuO/MnO or CuO/ZnO catalyst.The CO conversion of CuO/CeO2 catalyst at 413K and 433K are 85% and 97%,respectively.Comparing with the other two catalysts,CuO/CeO2 catalyst has larger surface area,pore volume,CO adsorption amount and reduction peak area,while lower CO desorption and reduction temperature.Besides there is a stronger metal-support interaction in CuO/CeO2 catalyst than in other catalysts.All these favour the activity of the catalyst.