1-Substituent-6-oxo-pyridazinone-tri-aceto glucosides arabinofuranoside and 1-substituent-6-oxo-benzopyridazinone-tri-aceto glucosides arabinofuranoside compounds were synthesized by one step reaction for the first time,The yields were 68%-83% and their structures were characterized by 1HNMR,IR and elemental analysis.