The human-induced vertical vibration serviceability of low-frequency and lightweight footbridges is studied based on the moving mass-spring-damper(MMSD) biodynamic model, and the mass damper(TMD) with different optimal model parameters being used to control the vertical vibration.First, the MMSD biodynamic model is employed to simulate the pedestrians, and the time-varying control equations of the vertical dynamic coupling system of the pedestrian-bridgeTMD are established with the consideration of pedestrianbridge dynamic interaction; and the equations are solved by using the Runge-Kutta-Felhberg integral method with variable step size. Secondly, the footbridge dynamic response is calculated under the model of pedestrian-structure dynamic interaction and the model of moving load when the pedestrian pace frequency is consistent with the natural frequency of footbridge. Finally, a comparative study and analysis are made on the control effects of the vertical dynamic coupling system in different optimal models of the TMD. The calculation results show that the pedestrian-bridge dynamic interaction cannot be ignored when the vertical human-induced vibration serviceability of low-frequency and light-weight footbridge is evaluated. The TMD can effectively reduce the vibration under the resonance of pedestrian-bridge, and TMD parameters are recommended for the determination by the Warburton optimization model.