Objectives:To observe the clinical effect on opioid-induced constipation of liver stagnation and spleen deficiency treated with the ultrasonic penetration of the No.1 constipation herbal formula at Tiānshū(天枢ST25).Methods:A total of 126 patients that were in compliance with the inclusion criteria were randomized into an acupoint group(41 cases),a Chinese medication group(42 cases)and a western medication group(43 cases).In the acupoint group,the ultrasonic penetration of the No.1 constipation herbal formula at bilateral Tiānshū(天枢ST25)were given.In the Chinese herbal medication group,the No.1 constipation herbal formula was prescribed for oral administration.In the western medication group,polyethylene glycol electrolyte powder was prescribed for oral administration.The treatment was given once a day,for 14 days totally.Before and after treatment,the constipation symptom score,the score of the patient assessment of constipation quality of life(PAC-QOL),the situation of nitric oxide synthetase(NOS)in serum were observed in each group.The safety indicators in the observation included diarrhea,allergic reaction,liver dysfunction,skin lesions,etc.Results:A total of 122 cases accomplished the trial.The total effective rate was 82.5%in the acupoint group,80.48%in the Chinese medication group and 78.04%in the western medication group.The constipation symptoms were all relieved in the three groups,indicating the statistical significance as compared with those before treatment(P<0.01,P<0.05).In the acupoint group and the western medication group,the improvements in the three symptom items,i.e.distention or scurrying pain in the chest,hypochondriac region or the bilateral sides of the abdomen,depression or irritability and poor appetite,were better than the western medication group(P<0.01,P<0.05).The improvements in all of the symptoms in the acupoint group were better than the Chinese medication group(all P<0.05).The PACQOL score was improved in each group after treatment and it was different significantly in
Objective:To observe the clinical therapeutic effect of ginger-isolated moxibustion on cancer-related fa tigue(CRF)in the patients with gastric cancer.Methods:The patients in the conventional treatment group accepted conventional chemotherapy.In the ginger-isolated moxibustion group,on the base of the conventional chemotherapy,ginger-isolated moxibustion was added at Shénquè(神阙CV8),Shàngwǎn(上脘CV13),Zhóngwǎn(中脘CV12),Qìhǎi(气海CV6]and Guānyuán(关元CV4).Chemotherapy for 3 weeks was as 1 cycle and 2 cycles of chemotherapy were observed.Results:After treatment,plasma cortisol(Cor)was increased and adreno-cortico-tropic-hormone(ACTH)decreased in the ginger-isolated moxibustion group,indicating the statistical differences as compared with the levels before treatment(P<0.05),and the differences in plasma Cor and ACTH were significant statistically between the two groups(P<0.05).After treatment,the score of each item of the revised fatigue scale was reduced in the ginger-isolated moxibustion group,indicating the statistical differences as compared with the score before treatment(P<0.05).The score of the revised fatigue scale was different statistically between the two groups(P<0.05).After treatment,the score of each of the items,i.e.fatigue,nausea&vomiting,pain,dyspnea,insomnia,anorexia,constipation,diarrhea and financial difficulty,was reduced in the ginger-isolated moxibustion group,indicating the statistical differences as compared with the score before treatment successfully(P<0.05).The differences were significant statistically in fatigue,nausea&vomiting,pain,dyspnea,insomnia,anorexia,constipation,diarrhea and economic difficulty between the two groups(P<0.05).Conclusion:Ginger-isolated moxibustion achieves a satisfactory effect on CRF in the patients with gastric cancer and deserves to be promoted in clinical practice.
