To investigate the phytochemical constituents of aboveground parts of Croton tiglium L. （family Euphorbiaceae）, its ingredients were isolated by repeated chromatography on silica gel, Sephadex LH-20, ODS and preparative HPLC. Their structures were identified based on 1D, 2D NMR and mass spectral analysis. A total of 10 phorbol esters were obtained. Among them, compound 1 （12-O-（2-methyl）butyryl-4ct-deoxyphorbol-β-isobutyrate） and compound 10 （20-formyl-4a-deoxyphorbol- β-acetate） were two new compounds, and the other eight were known compounds.
Croton crassifolius Geisel belongs to the genus croton of the family euphorbiaceae. By means of solvent extraction and repeated chromatorgraphy on silica gel, Sephadex LH-20 and HPLC, the ethanol extract of the roots of Croton crassifolius Geisel was chemically investigated, which led to the isolation of nine diterpenoids. By using spectroscopic analysis, their structures were identified as follows： Crassifolin P（1）, Crassifolin J（2）, 1,5,6-trimethyl-5-（2-（5-oxo-2,5-dihydrofuran-3-yl）ethyl）-1,2,3,4,5,6,7,8-octahydronaphthalene-1-carboxylate（3）, Penduliflaworosin（4）, isoteucvin（5）, Crassifolin G（6）, teucvin（7）, Chettaphanin I（8）, mallotucin D（9）. Among of them compound 1 was a new compound.
