A series of mesoporous silica with variable pore structures were prepared.The influence of mesoporous structure on drug release profiles was studied.It is found that mesoporous pore structure has a great effect on the drug release rate.The cubic pore structure MCM-48 has a faster drug release rate than that of MCM-41 system;while SBA-16 with 'cage-like' pore structure system has the lowest drug release rate.
This work describes a novel method to synthesize NaY zeolite at high temperature(100-140 ℃)by using NaY seeds solution as a silica source,which is also a method for the activation of silica source in the synthesis of NaY zeolite.Conventionally,the synthesis temperature of NaY zeolite from water glass is about 100 ℃,and higher temperature(>100 ℃)leads to the formation of impurity.However,this work shows that high-temperature synthesis(100-140 ℃)still exhibits a pure phase NaY.It is very interesting that,compared with conventional temperature,high-temperature in the synthesis of NaY zeolite has obvious advantages such as short crystallization time and high n(Si)/n(Al)ratio in the product.More importantly,this method is possible to extend to the synthesis of NaA,NaX,Ω,ECR-1and MOR.