The Carboniferous reservoir in KJ oilfield is a carbonate reservoir with extremely low porosity and permeability and high-pressure. The reservoir has severe heterogeneity, is deeply buried, has complex master control factors, is covered with thick salt, all of which result in the serious distortion of reflection time and amplitudes under the salt, the poor seismic imaging, and the low S/N ratio and resolution. The key to developing this kind of reservoir is to correctly predict the distribution of highly profitable oil zones. In this paper we start by analyzing the master control factors, perform seismic-log calibration, optimize the seismic attributes indicating the lithofacies, karst, petrophysical properties, and fractures, and combine these results with the seismic, geology, log, oil reservoir engineering, and well data. We decompose the seismic prediction into six key areas: structural interpretation, prediction of lithofacies, karst, petrophysical properties, fractures, and then perform an integrated assessment. First, based on building the models of faults and fractures, sedimentary facies, and karst, we predict the distribution of the most favorable reservoir zones qualitatively. Then, using multi-parameter inversion and integrated multi-attribute analysis, we predict the favorable reservoir distribution quantitatively and semi-quantitatively to clarify the distribution of high-yield zones. We finally have a reliable basis for optimal selection of exploration and development targets.