The synthesis and characterization of a series of peptide dendronswith glycin（Gly） and glutamate（Glu） as building blocks were described.The dendrons were prepared with convergent method by protection,deprotection and DCC coupling reactions.With the characterization of elemental analysis,（）1H-NMR,（）13C-NMR,FTIR,EI-MS and MAILD-TOF MS,the designed molecular structure was proved.It could be predicted that the obtained compounds will exhibit unique properties and potential applications in the fields of biology,medicine and so on.Further studies on the properties of these compounds are in progress.
An azyl group of ethylene diamine was protected by N-tert-butoxycarbonyl.The remaining azyl group then successively reacted with methyl acrylate, ethylene diamine and methyl acrylate again to afford the compound Boc-NH 2-(B-COOCH 3) 4 3 (AB-4).The ester groups and the Boc-end group of 3 were transferred to carboxylate 4 and azyl group 5 via hydrolyzation and deprotection respectively.The fan-shape dendron molecules with 16 exterior groups 6 were obtained by condensation of 4 and 5 in the presence of DCC.The dumbbell-like dendrimer molecules 7 could expediently prepared by coupling the dendrons with two functional groups of hexanedioyl chloride.The paper describes the synthesis procedures,reports the characterization results of FTIR、 1H-NMR、 13C-NMR and MALDI-TOF.Comparing with the PAMAM dendrimers from the divergent method, the synthesized compounds possess accurate structures and few defections.
H 2PtCl 6 was coordinated with the carboxyl-terminated G4.5PAMAM dendrimer molecules (PAMAMC) in aqueous solution,followed by reduction using NaBH 4 as reducer,and formed Pt-PAMAMC hybrid nano-particles.The stable multilayer films were obtained by fabricating diazo resin(DR) with these hybrid nanoparticles (Pt-PAMAMC) and PAMAMC,respectively.The films were subsequently irradiated under UV-light.It was found that the films from Pt-PAMAMC as polyanions exhibit stable frictional responses under the applied load,and the lubricative property of the films from Pt-PAMAMC hybrid nanoparticles is obviously superior to that of the films from dendrimer without platinum inside.
