Based on analyzing the changes of land use in Wuzhong District, Suzhou City from 2005 to 2008, temporal and spatial changes of land use from 2008 to 2020 were analyzed by using the model CLUE-S and, from the perspective of landscape ecology, future landscape pattern changes of land use in Wuzhong District were also quantitatively discussed by utilizing landscape indices. The results indicated that there was a large variation range of land use in Wuzhong District from 2005 to 2008 and massive farmland and woodland were transformed into construction land and gardens. Guided by the policy of saving intensive land and protecting farmland, future variation range of land use will get smaller obviously. The fragmentation degree for farmland, woodland and water area will get decreased but will get increased relatively for construction land. In general, all landscapes tend to a balanced development.
