Feline panleukopenia virus (FPV),belonging to the genus Parvovirus within the family Parvoviridae, infects and causes disease in carnivore species throughout the world. However, few epidemiological studies of this virus have been done in wildlife in China. The aims of this study were to determine the infection rate of FPV in captive tigers, lions and domestic cats. Serum samples were obtained from 207 tigers and 4 lions between 2002 and 2006 in different wildlife zoos of China,and 23 domestic cats, and further tested for antibodies against FPV by serum neutralization(SN) assay and hemagglutination-inhibition (HI) assay, whose results are consistent. A seropositive rate of 53.1% was found in tigers,25% in lions and 26% in cats. These results indicated that most of the felines had been infected with feline panleukopenia virus, and the virus may cause disease in carnivore species in China.
