A new deacid refined method of distillate oil, microwave irradiation, was put forward. The optimum conditions of the refined process are investigated. The volume ratio of solvent to oil is ((0.20~0.25)∶1), the pressure is0.04?MPa~0.06?MPa, the radiant time is 6?min under the constant pressure, microwave power is 375?W, settled for 25?min the acidity will be reduced from 170.4?mg/100?mL to 8.35?mg/100?mL, which is good enough to meet the best specification of GB, and the refined process has no effect on the quality of the distillate oil. The oil used in this study is common cut 2 distillate from Liaohe oil field. The recovery ratio can reach 99.3%.