Based on three years of long-term fixed-site field trial, the effects of differ- ent tillage and mulching modes on the yield and output value of tobacco and soil quality were investigated. The results showed that the yield and output value of to- bacco in tillage treatment were improved by 22.72 % and 37.23 % compared with non-tillage treatment, respectively; the yield and output value of tobacco in rotation treatment were improved by 1.83% and 19.41% compared with continuous cropping treatment, respectively; the yield and output value of tobacco in straw mulching treatment were improved by 3.55% and 2.4% compared with non-straw mulching treatment, respectively, which indicated that tillage, rotation and straw mulching could improve the yield and output value of tobacco to a certain extent; especially, the yield and output value of tobacco increased significantly after plowing under rotation conditions. The contents of available phosphorus （AP）, alkali-hydrolyzable nitrogen （AN）, organic matter （OM）, total nitrogen （TN） and total phosphorus （TP） in non- tillage treatment were 35.14%, 9.92%, 9.57%, 4.40% and 34.16% higher compared with tillage treatment; especially, under non-tillage conditions, soil pH and contents of available potassium （AK）, AP, AN,OM,TN,TP and total potassium （TK） in continu- ous cropping field were 2.01%, 48.68%, 73.09%, 11.45%, 7.71%, 7.31%, 47.68% and 11.78% higher compared with rotation field, indicating that non-tillage treatment and continuous cropping could improve the total content and available content of organic matter, nitrogen and phosphorus. Therefore, from the perspective of soil fer- tility improvement and sustainable tobacco production, continuous cropping under non-tillage conditions might be the most appropriate cropping pattern for local soil fertility improvement; aiming at improving the yield and output value of tobacco, green manure-tobacco→, green manure/wheat/maize→green manure-tobacco ro- tation might be the most appropriate cropping pat
