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周红宇

作品数:4 被引量:17H指数:2
供职机构:武汉市普爱医院更多>>
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青少年单侧鼻腔鼻窦肿瘤2例
2013年
The clinical data of two adolescents with unilateral nasal cavity neoplasm were analyzed.Both were male,one was 14-year-old and the other was 17.Both were complained of unilateral nasal obstruction and nasal discharge;The course of disease of the former was one month,and that of the latter was three month;both were found neoformation in unilateral nasal cavity in medical examination.Occupying lesion in unilateral nasalcavity and sinus were demonstrated in CT scan of two cases.Endoscopy surgery were operated in both cases,incisal opening in labiogingival groove was added in the latter.Pathology of the former was capillary hemangioma and the latter was rhabdomyosarcoma.No findings indicating recurrence has been observed in two cases under 6 months follow-up.Recognition at nasal cavity and paranasal sinus neoplasm in adolescent is essential so thatproper management can be initiated. Abstract:Summary The clinical data of two adolescents with unilateral nasal cavity neoplasm were analyzed.Both were male,one was 14-year-old and the other was 17.Both were complained of unilateral nasal obstruction and nasal discharge;The course of disease of the former was one month,and that of the latter was three month;both were found neoformation in unilateral nasal cavity in medical examination.Occupying lesion in unilateral nasalcavity and sinus were demonstrated in CT scan of two cases.Endoscopy surgery were operated in both cases,incisal opening in labiogingival groove was added in the latter.Pathology of the former was capillary hemangioma and the latter was rhabdomyosarcoma.No findings indicating recurrence has been observed in two cases under 6months follow-up.Recognition at nasal cavity and paranasal sinus neoplasm in adolescent is essential so thatproper management can be initiated.
周建华李艳妮许戈周红宇
关键词:鼻肿瘤鼻腔鼻窦青少年
87例外伤性歪鼻的手术矫治被引量:12
2009年
李艳妮韩前超周红宇
关键词:鼻畸形外伤鼻中隔鼻成形术鼻内镜
儿童良性增生性声带疾病手术疗效的嗓音声学分析被引量:5
2017年
目的:探讨嗓音声学分析在儿童良性增生性声带疾病中的应用及对手术疗效的评估。方法:采用Dr.speech软件,对93例良性增生性声带疾病患儿在术前及术后15d、30d进行嗓音声学分析,并与76例正常儿童进行对照比较。结果:良性增生性声带疾病组与正常对照组相比,基频微扰(Jitter)、振幅微扰(Shimmer)、噪声能量(NNE)升高而谐噪比(HNR)、信噪比(SNR)降低,各指标均差异有统计学意义;良性增生性声带疾病组术后15d、30d和术前比较,Jitter、Shimmer和NNE均下降,HNR和SNR升高,均差异有统计学意义;术后30d各参数值均恢复至正常水平。结论:嗓音声学分析能客观、定量地评价儿童嗓音的质量及手术疗效。
周红宇李艳妮许戈曹婧
关键词:儿童声带疾病嗓音声学
Th17相关细胞因子在CRSsNP中的表达及意义
2012年
目的:检测Th17细胞核转录因子RORC及细胞因子IL-17A、IL-22以及中性粒细胞标记MPO在慢性鼻-鼻窦炎不伴鼻息肉(CRSsNP)中的表达及其相关性,进而探讨Th17在CRSsNP发病机制中的作用及其与中性粒细胞炎症的关系。方法:实时定量方法检测17例CRSsNP患者筛窦黏膜及10例鼻中隔偏曲矫正患者下鼻甲组织中RORC、IL-17A及IL-22mRNA表达并探讨其相关性;免疫组织化学检测IL-17A+细胞的表达;ELISA检测MPO的表达并探讨其与Th17的相互关系。结果:RORC及IL-17A、IL-22mRNA在CRSsNP组中的表达较对照组显著上调且RORC、IL-17A及IL-22mRNA表达呈正相关,免疫组织化学证实CRSsNP组较对照组具有更高的IL-17A表达。CRSsNP组较对照组含有更高的MPO表达,然而MPO的表达与Th17相关因子表达无相关性。结论:Th17细胞以及中性粒细胞炎症反应可能共同参与了CRSsNP的发病,然而二者可能并无内在的相互作用。
王宝凤李本农曹婧周红宇李艳妮
关键词:鼻窦炎TH17MPO中性粒细胞
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