目的:评价女大学生心理健康状况与月经的相关性。方法:检索中英文数据库中所有月经异常女大学生进行心理状况自评的横断面研究,检索年限为建库至2023年12月31日。根据纳入、排除标准对文献进行筛选,并采用Revman软件对测量指标进行Meta分析。结果:纳入10篇文献,5850名受试者。Meta分析结果显示:1) 7篇文献报道了月经失调学生与月经正常学生SCL-90测量数据的差异,结果显示与月经正常女大学生相比,月经异常学生的心理状况评分显著升高[WMD = 0.21, 95%CI (0.17, 0.26), Z = 10.00, P P Purpose: To assess the relationship between mental health status and menstruation among female university students. Method: All literature for menstrual disorder of female university students assessed with symptom checklist-90 (SCL-90) was searched manually in both Chinese and English database. The literature analyzed in this study was published before Dec. 31st, 2023. The data were screened according to inclusion and exclusion criteria, and applied in Meta-analysis using software called Review Manager. Results: The study includes 10 literature and 5850 subjects. The result of Meta-analysis showed: 1) The differences of measurement data by SCL-90 between menstrual disorder and menstruation normal students was reported in 7 literature. The result showed menstrual disorder can significantly increase the scores of mental symptoms (WMD = 0.21, 95%CI (0.17, 0.26), Z = 10.00, P P < 0.00001). Conclusion: The mental health level of female university students with abnormal menstruation is significantly lower than that of female university students with normal menstruation. Universities should build a new model of psychological and physiological education for female college students to improve the quality of their physical and mental health.