In a model of intercellular calcium ion system oscillations, internal stochastic resonance(ISR) is investigated under the modulation of two parameters, viz., degree of extracellular stimulation β and leak rate k f. When either β or k f is subjected to a noise, ISR can occur. When noise is added to the two parameters simultaneously, internal stochastic bi-resonance(ISBR) occurs. The distance to the bifurcation point is found to be able to enhance or suppress the ISBR, and to affect the number of peaks of ISR.
The dynamic behavior of calcium ion oscillations was investigated when noise was injected to the system located in a steady state and an oscillatory state,respectively.It was found that noise can contribute to phenomenon of implicit or explicit internal stochastic resonance(IISR or EISR),and that distance to bifurcation point was a key factor for controlling IISR or EISR.Then an external signal was added to the system,the result shows that IISR or EISR can not occur,implying an external signal destroys the cooperation of internal signal and noise.Furthermore,the difference and the similarity were discussed between IISR and EISR.