目的:观察平肝活血方对合并卵圆孔未闭(PFO)-右向左分流(RLS)-Ⅰ级偏头痛患者的临床疗效。方法:采用回顾性病例系列研究方法,对190例合并PFO-RLS的偏头痛患者进行初步证候归纳,进而纳入61例肝风血瘀证且经平肝活血方干预的合并PFO-RLS-Ⅰ级偏头痛患者,对其临床信息进行分析,比较其干预前后14 d的头痛发作次数,以及入组后0、7、14、21 d各时点的头痛视觉模拟评分(VAS)。结果:肝风血瘀证是合并PFO-RLS偏头痛患者最常见的证型,占比为37.37%(71/190);与干预前比较,平肝活血方干预后患者头痛发作次数显著减少(P<0.01),干预后7、14、21 d VAS评分显著降低(P<0.01)。结论:平肝活血方可有效减轻合并PFO-RLS-Ⅰ级偏头痛患者的疼痛程度及发作次数。
This systematic review is aim to comprehensively evaluate the efficacy of acupoint stimulation in managing of post-stroke spasticity. The eligible randomized controlled clinical trials （RCTs） and quasi-randomized controlled clinical trials （quasi-RCTs） will be searched from the following databases： the Cochrane Central Register of Controlled Trials （CENTRAL）, MEDLINE, EMBASE, China National Knowledge Infrastructure （CNKI）, Chinese Scientific Journal Database （VIP）, Wanfang Database, Chinese BioMedical Literature Database （CBM）. The Cochrane risk of bias tool will be used to assess the trials. No patients or their family will be bothered in this systematic review, so there is no need for the permission of institutional review board （IRB）. The completed systematic review will be published in a peer-reviewed journal.
