Objective To discuss the relation between the expression of p73 and p63 gene and pathological diagnosis of neuro-epithelial tumor on the malignant degree and prognosis. Methods The bio-marking method and S-P immunohistochemical method were used to detected the p73 and p63. PBS was instead of 1 antibody as negative control. Results The difference positive expression in astrocytoma and 5 kinds of neuro-epithelial tumors. The positive rate was related with the malignant degree. Conclusion The p73 and p63 genes combined with pathological diagnosis could supply the certain diagnosis and assistant for the prognosis.
