[Objective] The research aimed to provide the reference for the precise formula and balanced fertilization of tobacco production in Fuquan City, Guizhou Province. [Method] 180 soil samples were gathered from Fuquan City by Global Position System (GPS) fixed position. The main nutrient contents and pH value were analyzed. [Result] The average contents of organic matter, available nitrogen, available phosphorus, available potassium in tobacco planting soil were 26.8 g/kg, 134.1 mg/kg, 35.9 mg/kg, and 222.1 mg/kg respectively, and the coefficient of vari- ation were 25.8%, 21.4%, 72.1%, and 55.3% respectively. The pH value of tobacco planting soil was 6.2, and the pH value coefficient of variation was 15.3%. [Conclu. sien] The organic matter, available nitrogen, available phosphorus, available potassi- um contents were abundant in the mass, but there were big difference among dif- ferent towns. The precise fertility types and precise fertility dosage should be deter- mined according to the main nutdent state and pH value of tobacco planting soil in Fuquan city.