Ethyl cellulose is coated on 3-aminopropyl silica gel,with optical resolution ability as chiral stationary phase(CSPs) for high-performance liquid chromatography is evaluated with a flow rate of 0.5 mL/min at 30℃.All the test solutes are detected at 254nm.Among 15 resolved racemates,6 chiral compounds could be separated in the normal phase condition,1 chiral compound in the reversed phase and 2 chiral compounds in acetonitrile condition.The results show that the chiral stationary phase possess good selectivity.