The effect of sucrose on nanometer Se0 in liquid phase was reported.Transmission electron microscope(TEM),laser light scattering image and Resonance Rayleigh Scattering(RRS) were used to study the configuration and stability of nanometer Se0 particles.The results show that sucrose solution modulated the assemble of nanometer Se0 particles and stabilized the Se0 particles in liquid phase.From the concentration of 1.07 to 42.8 μmol/L,the diameter of Se0 particles were 47—600 nm.However,in the presence of 1.0% sucrose solution,the major distribution range of Se0 diameter was 20—80 nm.Furthermore,the nanometer Se0 sol-gel could be preserved stably in sucrose solution at least for 2 months at 2—10 ℃.