Soybean Phytophthora root rot(PPR) that cause by Phytophthora sojae is one of the most serious diseases in the main soybean production area all over the world.In this manuscript,we analyzed the fungitoxicity of methyl bromide,propylene oxide,methyl iodide and carbonyl sulfide,their influences on the quality of soybean were also determined.Our results confirmed the efficacy of the four fumigants against Phytophthora sojae,their EC99 values were methyl bromide 21.24mg/L,propylene oxide 33.21 mg/L,methyl iodide 4.64 mg/L and carbonyl sulfide 46.73mg/L for 24h fumigation at 20℃.Moreover,quality analysis results showed that there were not significant differences between untreated and treated soybeans after 30d storage,indicating that fumigation with tested fumigants would be the candidates for control of Phytophthora sojae,especially methyl iodide.