Objective To observe the clinical efficacy of the needling method for regulating wei qi and strengthening brain on insomnia.Method Two hundred patients with insomnia were randomly divided into a group of regulating wei qi and strengthening brain(group A) and a group of normal acupuncture(group B)through random number table method,with 100 cases in each group.In group A,Baihui(百会 GV20),Dazhui(大椎 GV 14),Shenmai(申脉 BL62),Zhaohai(照海 KI 6) and auricular points Yuanzhong(缘中 AT 2,3,4i),and Shenmen(神门TF 4) were selected;and in group B,Sishencong(四神聪 EX-HN 1),Shenmen(神门 HT 7),and Sanyinjiao(三阴交 SP 6) were selected.Acupuncture was given on these points once daily for 15 days.Pittsburgh sleep quality index(PSQI) was used for scoring and curative effect was evaluated before and after treatment.Results The total effective rate was 89.0%(89/100) in group A and 65.0%(65/100) in group B with a very significant difference between the two groups(P〈0.01);the difference of PSQI scores before and after treatment was(-9.15±5.68)in group A and(-5.64±5.73)in group B,with a very significant difference before and after treatment in the two groups(P〈0.01).Conclusion The therapeutic effect of the needling method for regulating wei qi and strengthening brain on insomnia is superior to that of normal needling method.