In this study,we report the preparation and application of the AlC4Pc-magnetic silica nanotubes(AlC4Pc-MSNs),which was synthesized via alumina template membrane method.The synthesized outer-NH2-magnetic silica nanotubes(outer-NH2-MSNs)were characterized by TEM,SEM,EDS and SQUID.Besides these,UV-Vis absorption spectra and fluorescence spectra were also recorded,which further indicate that the AlC4Pc-MSNs have the similar features with free AlC4Pc.The AlC4Pc-MSNs not only have all the advantages of silica nanotubes,but also can be easily separated from the solution by external magnetic field.On the basis of the merits mentioned above,AlC4Pc-MSNs was used for the detection of pH value.Our work herein reveals that the outer-NH2-MSNs will be a promising platform for the applications of the targeting drug delivery,DNA transfection,selective separation,catalyst carriers and so on.
A novel fluorimetric method has been developed for the rapid determination of ncleic acids, based on that the catalytic activity of hemin is decreased due to the ion-association with Alcian blue 8GX and recovered when nucleic acids are added to the system. The change in the catalytic activity of hemin results in the fluorescence change of the hemin-catalyzed fluorogenic reaction system of p-hydroxyphenylacetic acid(p-HPA) and H 2O 2 and the fluorescence change of the system is proportional to the quantities of nucleic acids existing. The corresponding detection limits of the method are 0 91 ng/mL for CT DNA and 7 5 ng/mL for yeast RNA.
