目的:比较并评价在慢性牙周炎治疗中,Er:YAG激光的疗效是否优于根面平整术(Scaling and Root Planing,SRP)。方法:检索外文数据库Springerlink、OVID、Embase、Pubmed和中文数据库万方、维普、中国知网、中国生物医学文献数据库,收集自建库到2013年l2月公开发表的关于Er:YAG治疗慢性牙周炎随机对照试验的文献,随访时间不得少于三个月。采用Jadad法对文章质量进行评价,并使用Stata12.0对治疗三个月、六个月及十二个月后两组牙周探诊深度和临床附着水平的改变值进行Meta分析。采用I2检验检测不同研究间的异质性。结果:共有8篇文献符合纳入和排除标准,Meta分析结果显示三个月、六个月及十二个月后,Er:YAG组与SPR组相比,牙周探诊深度差异无统计学意义,附着水平的差值也无统计学意义。结论:Er:YAG激光治疗牙周炎的短中期临床疗效好,可作为SPR的辅助疗法甚至替代疗法,但目前尚无足够的证据证明Er:YAG激光的临床疗效优于SPR。由于纳入研究的数量有限,且只有2篇文献为高质量研究,因此,上述结论仍需更多高质量的研究进一步证实。
To investigate the bacterial colonization on zirconium oxide and titanium surfaces in vivo quantitatively using a confocal laser scanning microscope （CLSM）. Ten samples of zirconium oxide ceramic and commercially pure titanium were fabricated and polished using silicon carbide abrasive paper. One sample from each group was evaluated topographic pattern under a scanning electron microscope. One sample from each group was to evaluate roughness using a profilometer. Eight volunteers were selected. The samples were cemented at the buccal surfaces of upper first molars. All samples were removed after 48 hours, immersed in SYTO-9 and propidium iodide fluorescent to stain for adherent bacteria and obseIved with CLSM. Fewer bacteria were observed in zirconia group than titanium group. However, there was no statistical difference between two groups. The experimental results demonstrate that zirconium oxide may be considered as a promising material for dental implant abutments.
