A new cardenolide, toxicarioside E （1）, was isolated from the latex ofAntiaris toxicaria （Pers.） Lesch （Moraceae）. Its structure was elucidated on the basis of spectral data and chemical evidence. Compound 1 showed significant cytotoxicity against K562 and SGC-7901 cell lines in vitro by MTT method with the IC50 value of 0.026 and 0.027 μg/mL, respectively.
为探讨小叶米仔兰（Aglaia odorata var. microphyllina）中的抗菌活性成分,从其枝条的乙醇提取物中分离得到6个化合物,通过波谱分析,分别鉴定为：4（15）-桉叶烯-1β,7,11-三醇 （1）、4α,10β,11-三羟基-1,5-反-愈创木烷-6-烯（2）、6,15α-环氧-1β,4β-二羟基桉烷（3）、2-羟基-丁二酸-1-甲酯（4）、巴西红厚壳素（5）和胡萝卜苷（6）。以上化合物均为首次从该植物中分离得到,其中化合物1、2、4和5为首次从米仔兰属植物中分离得到。用滤纸片琼脂扩散法测定了化合物1～5的抗菌活性,结果显示化合物4和5对金黄色葡萄球菌有抑制作用。
Phytochemical investigation on the stems of Trigonostemon heterophyllus led to the isolation of a new diterpen...
Yi-Xing Li~(a,c,+),Wen-Li Mei~(a,b,+),Wen-Jian Zuo~(a,b),You-Xing Zhao~(a,b),Wen-Hua Dong~(a,b) and Hao-Fu Dai~(a,b,*) a.Hainan Key Laboratory for Research and Development of Tropical Natural Products,Institute of Tropical Bioscience and Biotechnology.Chinese Academy of Tropical Agricultural Sciences.Haikou 571101,Hainan,P.R.China b.Hainan Key Laboratory for Research and Development of Natural Product from Li Folk Medicine,Haikou 571101, Hainan.P.R.China c.College of Agriculture,Hainan University.Haikou 570228.Hainan.P.R.China
