This study aimed to explore the optimum drip irrigation belt arrangement mode for mechanically-harvested cotton in Xinjiang. The Xinluzao 61 was selected as the experiment material, and the effects of two different drip irrigation modes（6 cotton rows with 2 drip irrigation pipes under plastic film, 6 cotton rows with 3 drip irrigation pipes under plastic film） on the growth and yield of Xinluzao 61 were investigated under mechanical harvest. The results showed that under the mode of 6 cotton rows with 2 drip irrigation pipes, the growth rate of edge-row cotton was lower in the early growth period, and its emergence rate and agronomic traits were all lower than those of the interior-row cotton; under the mode of 6 cotton rows and 3 drip irrigation pipes, the difference in cotton growth between edge and interior rows was smaller. The yield and benefit under the mode of 6 cotton rows with 3 drip irrigation pipes were higher than those under the mode of 6 cotton rows and 2 drip irrigation pipes by 255 kg/hm^2 and 1 500 yuan/hm^2, respectively. Therefore, the cultivation mode of 6 cotton rows with 3 drip irrigation pipes under plastic film should be promoted in the production.
