目的：研究前列腺癌患者术前焦虑和术后生活质量评估的相关性。方法选取32例行前列腺癌根治术的患者，在其术前1d，采用焦虑状态-特质评分问卷（the Stata-Trait Anxiety Inventory，STAI）进行焦虑评估；在术后1个月，采用前列腺癌治疗功能评价（the functional assessment of cancer therapy-prostate, FACT-P）问卷，对其生活质量进行调查。通过SPSS软件对患者的术前焦虑和术后生活质量评估进行相关性分析。结果患者的术前焦虑评分为59.0＆#177;7.3，术后生活质量评估为64.5＆#177;7.4。术前焦虑和术后生活质量评估呈线性负相关关系（r=-0.58，P＜0.05）。结论前列腺癌患者的术前焦虑和术后生活质量评分呈负相关关系，根据焦虑评分状况积极地进行围手术期的心理干预，加强患者与家人朋友的沟通交流，对临床治疗及术后恢复具有积极的意义。
目的研究前列腺癌患者围手术期心理干预和术后生活质量评估的相关性。方法选取107例行前列腺癌根治术的患者，随机分成实验组和对照组，在术前采用焦虑状态一特质评分问卷（the Stata．Trait Anxiety Inventory，STAI）进行焦虑评估；实验组在其围手术期进行心理干预，在术后一个月，对两组采用前列腺癌治疗功能评价（the functional assessment of cancer therapy-prostate，FACT-P）问卷，对其生活质量进行调查，对患者的术前焦虑和术后生活质量评估进行相关性分析。结果两组术前的STAI及其他各项观察指标无显著性差异（P〉0．05），术后实验组的FACT-P评分较对照组有显著性差异（尸〈0．05），实验组的术后生活质量明显优于对照组，其中情感状况的分值有显著差异（P〈0．05）。结论前列腺癌患者的围手术期心理干预有助于术后生活质量。在手术前根据焦虑评分状况制定围手术期的心理干预，对临床治疗及术后恢复具有积极的意义。
Erythropoietin(EPO) is a circulating glycosylated protein hormone and has been implicated in the development and progression of non-hematopoietic tissue tumors.The objective of the present study was to determine if the EPO rs576236 polymorphism was associated with the risk of adrenal tumors.We genotyped the EPO rs576236 polymorphism in a case-control study of 288 adrenal tumor patients and 456 cancer-free controls by using the TaqMan method,and assessed the association between the polymorphism and the adrenal tumor risk by logistic regression.Furthermore,95%confidence interval(CI) was used to assess the genetic association between the polymorphism and the risk of adrenal tumor.Compared with the TT genotype,the TC genotype had a significantly increased risk of adrenal tumor[adjusted odds ratio(OR) = 1.24,95%CI = 1.12-2.22].Furthermore a significantly increased risk of adrenal tumor was found in the combined variant genotypes TC+CC compared with the TT genotype(adjusted OR = 1.17,95%CI = 1.12-2.21).Our present study suggests that the rs576236 polymorphism of EPO confers susceptibility to adrenal tumor in the Chinese population.
