Chemical vapor generation(CVG) is an important sample introduction technique,and is widely used for atomic spectrometry for its enhanced sensitivity and selectivity.In the past 30 years,inductively coupled plasma mass spectrometry(ICP-MS) has become a widely used and the most sensitive instrument for(ultra-)trace element determination and elemental speciation.A review of applications of this state-of-the-art coupling of CVG and ICP-MS is presented.Discussion is focused on its applications for both element determination and speciation,including hydride generation,cold vapor generation,photochemical vapor generation,alkylation,and electrochemical vapor generation.In addition,recent studies undertaken isotope dilution calibration in CVG-ICPMS for achieving improved accuracy and precision are summarized,and the future perspectives are discussed.
