We review our recent theoretical advances in quantum information and many body physics with cold atoms in various external potential, such as harmonic potential, kagome optical lattice, triangular optical lattice, and honeycomb lattice. The many body physics of cold atom in harmonic potential is investigated in the frame of mean-field Gross-Pitaevskii equation. Then the quantum phase transition and strongly correlated effect of cold atoms in triangular optical lattice, and the interacting Dirac fermions on honeycomb lattice, are investigated by using cluster dynamical mean-field theory and continuous time quantum Monte Carlo method. We also study the quantum spin Hall effect in the kagome optical lattice.
