Purpose: To report an unusual case of IgG4-related Mikulicz's disease associated with thyroiditis.Case report: We describe a 25-year-old Chinese man who presented with bilateral, painless swellings of the lachrymal glands, parotid glands, and thyroid nodules. The patient underwent left-sided dacryoadenectomy and the diagnosis of IgG4-related Mikulicz's disease was pathologically confirmed.The size of the right-sided lachrymal gland and parotid glands recovered fundamentally after one month of glucocorticoid therapy.Conclusion: IgG4-related Mikulicz's disease associated with thyroiditis should be considered in the differential diagnosis of bilateral swellings of lachrymal glands, salivary glands, and thyroid nodules. Surgical excision is recommended in order to treat the tumor and to ensure the pathological diagnosis. Glucocorticoid therapy should be considered in association with surgery after removal.
INTRODUCTIONDiabetes mellitus （DM） is a global disease, the number of patients of which is predicted to rise to about 380 million by 2025 by the World Health Organization （WHO）. Diabetic retinopathy （DR） is one of the most sigificant complications in DM and the first cause of irreversible blindness of adults in the world It occurs in 90% of patients after 20-30y from the diagnosis of DM, and about 5 million individuals have DR, which is responsible for approximately 5% of blindness worldwide.
