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国家教育部博士点基金(200802841030)

作品数:3 被引量:21H指数:3
相关作者:胡冠九王心如刘红玲郝英群于红霞更多>>
相关机构:南京医科大学南京大学江苏省环境监测中心更多>>
发文基金:国家教育部博士点基金国家自然科学基金国家重点基础研究发展计划更多>>
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3 条 记 录,以下是 1-5
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太湖湖体有机污染物分布及蓝藻水华的次生影响
近年来,太湖的营养元素分布和水华形成机理得到了广泛关注,然而,对于湖体中有机污染物的分布,特别是蓝藻水华对其产生的次生影响情况知之甚少。本研究利用同柱萃取并逐级分离的方法对太湖不同湖区不同年份(2008年到2010年)有...
史薇王书航苏冠勇于南洋韦斯于红霞姜霞
关键词:太湖有机污染物水华暴发
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Probabilistic ecological risk assessment for three chlorophenols in surface waters of China被引量:7
2012年
Individual and combined assessment of risks of adverse effects to aquatic ecosystems of three chlorophenols(CPs),including 2,4dichlorophenol(2,4-DCP),2,4,6-trichlorophenol(2,4,6-TCP) and pentachlorophenol(PCP),were conducted.A probabilistic approach based on the concentrations of CPs in surface waters of China was used to determine the likelihood of adverse effects.The potential risk of CPs in surface waters of China was determined to be of concern,especially PCP and mixtures of CPs.The risks of adverse effects were examined as the joint probabilities of exposure and response.The joint probability for PCP was 0.271 in the worst case and 0.111 in the median case,respectively.Based on the cumulative probability,5% of aquatic organisms included in the assessment would be affected 21.36% of the time in the worst case and 5.99% of the time in median case,respectively.For the mixtures of CPs,the joint probability were 0.171 in the worst case and 0.503 in median case,respectively and 5% of species would be affected 49.83% of the time for the worst case and 12.72% in the median case,respectively.Risks of effects of the individual CPs,2,4-DCP and 2,4,6-TCP were deemed to be acceptable with a overlapping probability of 0.1 with 5% of species being affected less than 4% of the time.
Liqun XingHongling LiuJohn E GiesyXiaowei ZhangHongxia Yu
关键词:CHLOROPHENOLS
沿海三市饮用水源水内分泌干扰毒性研究被引量:7
2011年
近十多年来,江苏沿海化工产业发展迅速,化工废水的长期排放对水生生态系统及人群健康构成潜在威胁。采用非洲猴肾细胞(CV-1)核受体介导的体外转录激活试验方法,对中国东部沿海A、B、C三市的6个水源地进行了拟雌激素活性调查研究。结果表明:C市2处水源水的有机提取物在枯水期、平水期和丰水期均无拟雌激素活性检出,水质较好;A市的水源水提取物在枯水期具有明显的拟雌激素活性;B市的3处水源水有机提取物在3个季节均表现出显著的拟雌激素活性;雌激素活性当量计算结果表明,点位B-3在枯水期的当量浓度高于毒性限值,对水生生物的内分泌系统易造成威胁,应引起有关部门关注。另外,研究结果显示,CV-1细胞受体转录激活试验是一种筛选和分析环境样品的具有拟雌激素活性的快速和有效的方法,值得进一步推广和应用。
张凤仙胡冠九郝英群刘红玲王心如于红霞
关键词:饮用水源水内分泌干扰
江苏省饮用水源水潜在健康损伤筛查及评价
目前,针对饮用水源水这类微污染水体的监测和评价,环境管理部门还是主要依赖化学分析手段,重点关心国家水质标准中规定的化合物是否超标,至于是否存在健康危害还没有引起重视,缺乏针对低污染水体、有关健康损伤的指标筛查研究。本研究...
于红霞胡冠九韩晓冬王心如
关键词:饮用水源水生殖毒性
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Reproductive toxicity of organic extracts from petrochemical plant effluents discharged to the Yangtze River,China被引量:7
2010年
Water pollution of the Yangtze River in China became one of challenges that the government is facing today. Increasing numbers of petrochemical plants were built along the river in past decades, and numbers of organic chemicals were discharged into the river. Our goal was to establish in vitro system on rat sertoli cells, spermatogenic cells and leydig cells to investigate the reproductive toxicity potential induced by organic extracts from petrochemical effluents. Our results showed that the organic extract depressed the viability (p 〈 0.01) and destroyed the plasma membrane integrity of sertoli cells and spermatogenic cells to a certain degree. Accordingly, proportion of early apoptotic sertoli cells and late apoptotic spermatogenic cells increased significantly. Although significant morphological changes were not detected for leydig cells, the extract was observed to inhibit their testosterone production (p 〈 0.01). Sertoli cells and sperrnatogenic cells appeared to be more sensitive and maybe the main targets of the key toxins. These results suggested that the in vitro system on rat testicular cells may be useful to predicate reproductive toxicity potential of organic extracts from petrochemical effluents. More attention should be paid to the petrochemical effluents, because long-term accumulation of these organic compounds in organisms may cause spermatogenesis malfunction and testosterone reduction.
Xiaoyi WangWei ShiJiang WuYingqun HaoGuanjiu HuHongling LiuXiaodong HanHongxia Yu
关键词:WASTEWATER
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