The rolling massage is one of the most important manipulations in Chinese massage,which is expected to eliminate many diseases.Here,the effect of the rolling massage on a pair of particles moving in blood vessels under rolling massage manipulation is studied by the lattice Boltzmann simulation. The simulated results show that the motion of each particle is considerably modified by the rolling massage,and it depends on the relative rolling velocity, the rolling depth,and the distance between particle position and rolling position. Both particles'translational average velocities increase almost linearly as the rolling velocity increases,and obey the same law. The increment of the average relative angular velocity for the leading particle is smaller than that of the trailing one. The result is helpful for understanding the mechanism of the massage and to further develop the rolling techniques.