Aim: The tuberomammillaiy nucleus ( TM) , located in the posterior hypothalamus, is the sole seat of histamine...
Zhu - Ge Zheng - Bing Wu Deng - Chang Wang Shuang Jin Chun - Lei Chen Zhong Department of Pharmacology, School of Medicine, Zhejiang University Hangzhou 310058
Aim: The piriform cortex (PC) is considered to be critically involved in the genesis of lirabic seizures. In t...
Zhu - Ge Zheng - Bing Zhu Yuan - Yuan Wu Deng - Chang Wang Shuang Chen Zhong Department of Pharmacology, School of Medicine, Zhejiang University, Hangzhou 310058
We described a female patient with insulinoma who experienced recurrent episodes of automatism, confusion and convulsion. Furthermore, her electroencephalography (EEG) findings resembled the pattern in complex partial seizures with secondary generalization. The interictal EEG showed spikes and sharp waves, as well as focal slowing over the left temporal lobe, and the ictal EEG revealed generalized spikes and sharp waves associated with diffused slowing. She was initially misdiagnosed as pharmacoresistant epilepsy. After the insulinoma was found and surgically removed, her EEG turned normal and she was seizure-free during the 4-year follow-up. This report highlights the need for careful reassessment of all seizures refractory to medication, even for the oatients associated with eoileotiform discharges on EEG.
Shuang WANG Hai-tao HU Shu-qun WEN Zhong-jin WANG Bao-rong ZHANG Mei-ping DING
Aim: To elucidate the possible role of carnosine in pentylenetetrazol (PTZ) -induced seizures using both histi...
Zhu Yuan - Yuan Zhu - Ge Zheng - Bing Wu Deng - Chang Wang Shuang Chen Zhong Department of Pharmacology, School of Medicine, Zhejiang University Hangzhou 310058