Wetland stores substantial amount of carbon and may contribute greatly to global climate change debate. However, few researches have focused on the effects of global climate change on carbon mineralization in Zoige alpine wetland, Qinghai-Tibet Plateau, which is one of the most important peatlands in China. Through incubation experiment, this paper studied the effects of temperature, soil moisture, soil type (marsh soil and peat soil) and their interactions on CO2 and CH4 emission rates in Zoige alpine wetland. Results show that when the temperature rises from 5℃ to 35℃, CO2 emission rates increase by 3.3-3.7 times and 2.4-2.6 times under non-inundation treatment, and by 2.2-2.3 times and 4.1-4.3 times under inundation treatment in marsh soil and peat soil, respectively. Compared with non-inundation treatment, CO2 emission rates decrease by 6%-44%, 20%-60% in marsh soil and peat soil, respectively, under inundation treatment. CO2 emission rate is significantly affected by the combined effects of the temperature and soil type (p 〈 0.001), and soil moisture and soil type (p 〈 0.001), and CH4 emission rate was significantly affected by the interaction of the temperature and soil moisture (p 〈 0.001). Q10 values for CO2 emission rate are higher at the range of 5 ℃-25℃ than 25 ℃-35℃, indicating that carbon mineralization is more sensitive at low temperature in Zoige alpine wetland.