Aeolian sediments are widely distributed in the Qaidam Basin, northeastern Qinghai-Ti^tan Plateau (QTP). The pale(xiunes are mainly located at the southeastern, middle and southwestem Qaidam Basin. However, ages ofpaleodunes in the middle and southwestern Qaidam Basin have not been well studied, although they are close to and might connect to the evolution of salt lakes in the cenWal basin. In this study, we use single aliquot regeneration (SAR) protocol of Optically Stimulated Luminescence (OSL) to date the dune sand in these two regions. The results show that: (1) Sand accumulation in these regions started at ca. 4-3 ka and lasted to ca. 0.5 ka when they were stabilized, due to the arid climate in the late Holocene. (2) The underlying fluvial sand was fomaed during deghcialion at 12.6±0.8 ka. (3) The stabilization pe- riods of the paleodunes correspond to stages of glacier advance in the northeastem QTP, during which lower temperatures caused the decrease of evapomlion and increase of the effective moisttwe, leading to an increase of vegetation cover and stabilizalion of the dunes.