Three full-substituted calix[6]arenes containing the picolinamide groups were synmesized and characterized by IR, ^1HNMR and MS, after series reactions, including lower rim etherification, upper rim ipso-nitration, reduction, amidation.
Dong Qing LIU Ya Qing FENG Hao Hui GU Wen Liang XU
The new fused quinazoline spiro-heterocyclic compounds were synthesized by combining the fused thiazolidone and quinazoline structure with spiro-heterocyclic structure for the purpose to get novel bio-active compounds. Dipolar azomethine ylides reacted with dipolarphile 2-arylmethylene-9-benzylidene-5-phenyl-6,7,8,9-tetrahydro-5H-thiazolo[2,3-b]quinazoline-3-one via 1,3-dipolar cycloaddition to give nine fused quinazoline spiro-heterocyclic compounds. The configuration and conformation of the products were determined by elementary analysis, 1H NMR, IR and X-ray crystal analysis. The results also revealed that the reaction was stereospecific.
Three novel calix[4]（aza）crown deravatives have been synthesized, including a new [2]pseudorotaxane in which calix[4]- azacrown behaves as a stopper, a novel ＇tren＇ type calix[4]azacrown and a novel ＇spiro＇ type calix[4]azacrown containing moroholine unit. The structures of these compounds have been confirmed by NMR and MS.
Zhi Qiang Shi Ya Qing Feng Wen Xiang Wang He Wen Wang
