Objective To study the ability of construction of bone tissue and vessels in vitro by the co-culture system in...
Guo Shangchun~1,Chen Xin~2,Wang Jinwu~(3*),Rui Biyu~2,Sun Hui~2,Dai Kerong~3 I.Shanghai Institue for Microsurgery of Extermities,The Sixth People’s Hospital Affiliated to Shanghai Jiaotong University,Shanghai 200233,China 2.Department of Orthopedics,The Sixth People’s Hospital Affiliated to Shanghai Jiaotong University,Shanghai 200233,China 3.Department of Orthopedics,The ninth People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine,Shanghai 200011,China
Neuromuscular electrical stimulation has been studied to be a method of prophylaxis for deep venous thrombosis by activating the calf muscle pump. However, there is little evidence of the effects of different stimulating parameters on hemodynamics and comfort levels. The objective of this paper is to compare the effects of different stimulating parameters(current amplitude, pulse-width) on hemodynamic alterations of the popliteal vein and the comfort levels in a group of fourteen healthy subjects. Doppler ultrasound detection of peak venous velocity and blood volume were taken from baseline, twelve sequential electrical stimulations and foot dorsiflexion for each subject. A visual analogue scale was used to assess the subjects' pain perception of neuromuscular electrical stimulation. The results showed that peak venous velocity and blood volume augmented as current amplitude and pulse-width increased while pain level also increased. A compromise was reached that parameters consisting of an amplitude of 10 m A and a pulse-width of 500 μs would obtain a high-peak venous velocity and blood flow volume with a relatively comfortable perception. In addition, parameters consisting of an amplitude of 20 m A and a pulse-width of 300 μs were also shown to be a promising choice. However, further studies need to be done to validate and enrich these findings.
