国家自然科学基金(81271866) 作品数:3 被引量:12 H指数:2 相关作者: 彭鸿娟 夏菁 何成 魏海霞 曾科 更多>> 相关机构: 南方医科大学 更多>> 发文基金: 国家自然科学基金 广东省大学生创新实验项目 广东省科技攻关计划 更多>> 相关领域: 医药卫生 生物学 更多>>
弓形虫利用宿主细胞资源合成磷酸化蛋白的研究 刚地弓形虫是一种广泛分布的专性细胞内寄生原虫,它几乎可以寄生于所有的有核细胞。弓形虫以纳虫泡(parasitophorous vacuole,PV)的形式寄生于宿主细胞内。纳虫泡随着弓形虫的入侵而开始逐渐形成,其膜(pa... 陈艾媛 魏海霞 彭鸿娟文献传递 刚地弓形虫低水平DNA甲基化的检测及结果 DNA甲基化是指在甲基化酶(DNA methyltransferase,DNMT)的作用下,将1个甲基添加在DNA分子的碱基上。DNA甲基化可引起染色质结构、DNA构象、DNA稳定性及DNA与蛋白质相互作用方式的改变,从... 魏海霞 陈艾媛 彭鸿娟Toxoplasma gondii ROP18 suppresses IFN-γ/STAT1 pathway by targeting NMI in HEK293T cells Objectives: Several studies have shown that Toxoplasma gondii has developed means to effectively inhibit the h... Jing Xia Hongjuan Peng关键词:TOXOPLASMA GONDII NMI PATHWAY 文献传递 弓形虫感染与不良妊娠结局关系的Meta分析 <正>刚地弓形虫是一种可以广泛寄生于人和动物的原虫,同时能引起人兽共患的弓形虫病。人体通过先天性和获得性两种途径感染,先天性弓形虫感染可引起流产、死胎、早产、新生儿死亡及畸形等不良妊娠结局。本文采用Meta分析的方法,探... 李雪兰 魏海霞 彭鸿娟文献传递 弓形虫ROP2蛋白在纳虫泡膜定位研究 弓形虫(Toxoplasma gondii)棒状体分泌的ROP2蛋白对弓形虫侵染宿主细胞起着重要作用,并能诱导机体产生保护性抗体IgG、IgA等,对弓形虫病诊断及感染机制的研究有重要意义。本研究通过将重组质粒pET-32... 张丽 廖启彬 胡琳 彭鸿娟Function analysis of interaction between host cell Vimentin and T. gondii ROP18 Objectives: Vimentin, a class III intermediate filament protein, is involved in many cellular processes. Recen... Cheng He Hongjuan Peng关键词:TOXOPLASMA GONDII VIMENTIN 文献传递 Rac1’s Regulation on Host Cell Cytoskeleton Reorganization affects Toxoplasma gondii Invasion Efficiency Objectives: Rac1 is a small GTPase in Rho family and plays an important role in the cytoskeleton reorganizatio... Haixia Wei Xiaoshuang FengDepartment of Pathogen Biology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University Shengqun Deng Aiyuan Chen Shicheng Jiang Cheng He Jing Xia Xiaojun Wang Hongjuan Peng关键词:RAC1 CYTOSKELETON PHOSPHORYLATION 文献传递 Secretion and Distribution of Rhoptry Protein 16 during Toxoplasma gondii Invasion into Host Cells Objectives: To detect the secretion and localization of Toxoplasma gondii Rhoptry Protein 16(ROP16) during inv... Shichen Jiang Haixia Wei Cheng He Shengqun Deng Jing Xia Hongjuan Peng关键词:TOXOPLASMA GONDII RHOPTRY PROTEIN POLYCLONAL IMMUNOFLUORESCENCE 文献传递 Molecular toxoplasmosis diagnostics:A systematic review and meta-analysis Objectives: To update the molecular toxoplasmosis diagnostics that have been developed,a systematic review and... Shengqun Deng Lei Yuan Jiarui Yao Shichen Jiang Jing Xia Qiang Huang Ling Kong Lijuan Zhou Hongjuan Peng关键词:TOXOPLASMA GONDII DIAGNOSTIC DIAGNOSTIC POLYMERASE 弓形虫感染与不良妊娠结局关系的Meta分析 刚地弓形虫是一种可以广泛寄生于人和动物的原虫,同时能引起人兽共患的弓形虫病。人体通过先天性和获得性两种途径感染,先天性弓形虫感染可引起流产、死胎、早产、新生儿死亡及畸形等不良妊娠结局。本文采用Meta分析的方法,探讨弓形... 李雪兰 魏海霞 彭鸿娟