The effect of different kinds of wood and wood material on mammal growth and physiology index as interior material was discussed. The results showed that: The number of erythrocyte of the female mice in wood house is more than that in aluminum and concrete ones; The estradiol contents of the female mice in wood house is higher than that in concrete house, it indicated that wood house had a accelerated effect on mice reproduction; Contents of the growth hormone of the female mice is the highest in concrete house and the lowest in plywood house, and middle in house with %Pinus koraiensis% and %Betula platyphylla% timber; Growth hormone of male mice is not difference among these house;The phagocytizing indexes of the mice in different house is various and it is higher in wood house than that in aluminum and concrete ones. Therefore wood and wood material house had a adjusting effect on mammal growth and physiology index.