Three new sesquilignans,1-3,a new sesquiterpenoid,4,and three known compounds were isolated from the stem barks of Illicium simonsii.The structures of new compounds(1-4)were elucidated by spectroscopic methods.A biosynthetic pathway was proposed for simonsienols A-C(1-3).Anti-AChE activity and anti-BuChE activity were evaluated for all compounds except forα-cadinol ethyl ether(4).As a result,isodunnianol(7)exhibited anti-AChE activity with an IC50 value of 13.0μM.
Chuan-Fu DONGLei LIUHuai-Rong LUOXiao-Nian LIZheng-Ye GUANYi-Fen WANG
Seven new monoterpene phenyl ethers,namely micranthumnins A-G(1-7),were isolated from the stem bark of Illicium micranthum(Illiciaceae).Their structures were elucidated by comprehensive spectroscopic analyses including MS,IR,1D and 2D NMR.All compounds were evaluated for their anti-AChE activities.
Zheng-Ye GUANChuan-Fu DONGa Li GAOJia-Ping WANGShi-De LUOYi-Fen WANG
