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国家自然科学基金(H1408)

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Effect of Different Pretreatments to Post-space on Bonding Strength of Fiber Posts Luted with a Self-adhesive Resin Cement
2013年
The effects of different post-space pretreatments on the retentive force of fiber posts cemented with a self-adhesive resin cement were investigated. Twenty-eight single-canal premolars were obturated by Resilon using warm vertical compaction and treated with distilled water, 2.5% NaOCl, 17% EDTA and 2.5% NaOCI; or 17% EDTA, 2.5% NaOCI, and ultrasonic agitation (U/E/N treatment). Subsequently, radicular dentin surfaces were observed under scanning electron microscopy (SEM). RelyX Fiber Posts were cemented in the treated canals by using RelyX U100, and thin-slice push-out test and SEM observation of coronal and apical regions of the specimens were performed. Data were analyzed using two-way ANOVA and Tukey's HSD post- hoc tests, and the percentage of failure type was calculated. Ultrasonic/EDTA/NaOC1 irrigation showed the maximum effectiveness in removing the smear layer and debris on the dentin surface. The apical bond strength of the experimental groups was significantly higher than that of the control group (P〈 0.05). Adhesive failure between cement and dentin was the most common mode of failure. No obvious RDIZ or resin tag was detected. Chemical irrigants facilitated the bonding of these fiber posts, and ultrasonic activation improved retention. Future studies should evaluate the effectiveness of irrigation on fiber post push-out strength in fatigue cycling condition.
夏勇程祥荣
关键词:RESILON
诱导性多能干细胞在牙周组织重建领域的应用进展被引量:1
2016年
把特定的细胞因子负载到病毒上,再导入成熟体细胞,可将已分化的细胞重编程为诱导性多能干细胞(Induced pluripotent stem cells,iPS cells),iPS细胞能够快速增殖同时长期保持未分化状态,并可被诱导形成多种成熟体细胞、组织及器官。可通过组织工程的方法,将iPS细胞与特定细胞因子联合培养,与合适的细胞支架结合,通过细胞的增殖、分化、矿化沉淀,启动成骨及成血管过程,修复缺损的牙周组织。本文对iPS细胞的来源、培养方法,组织工程相关的细胞因子、细胞支架,及iPS细胞在牙周组织重建领域的应用进展作一系统综述。
陈靓雯晏奇施斌
关键词:IPS细胞细胞因子细胞支架
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