Salt and drought tolerance, high yield and quality, disease and pest resistance of cotton varieties are new requirements for the current situation in cotton production. Hengyou 12 is a transgenic Bt cotton variety bred by hybridizing JD 28 (interspeciflc progeny of upland cotton, sea-island cotton, wild cotton species) as female parent with GK55 (transgenic Bt cotton variety) as male parent. The combining of parents was based on the complementary principle of parental traits. Hengyou 12 with strong heterosis was selected under disease stress, pest stress, salt stress and drought stress. This variety has many excellent characteristics, such as good resis- tance to diseases and pests, high yield, excellent quality, strong drought resistance and salt tolerance. 'Hengyou12' was approved by Hebei Province in 2015, and is suitable for planting in middle and south areas of Hebei and similar ecological areas in the Yellow River basin.