Two pyrazoline derivants 1-(2-benzothiazole)-3-phenyl-5-(3-thiophene)-2- pyrazoline (BPTP) and 1-(2-benzothiazole)-3-(2-thiophene)-5-phenyl-2-pyrazoline (BTPP) have been synthe- sized and their crystal structures were determined by X-ray single-crystal diffraction. Crystal of BPTP belongs to triclinic, space group P1 with a = 9.4430(11), b = 9.9384(13), c = 9.9394(13) ?, α = 83.107(10), β = 79.947(10), γ = 70.221(7)o, V = 862.42(19) ?3, Z = 2, Dc = 1.392 g/cm3, μ(MoKα) = 0.316 mm-1, F(000) = 376, λ = 0.71070 ?, (?ρ)max = 0.348, (?ρ)min = –0.481 e/?3, the final R = 0.0407 and wR = 0.1055 for 2844 observed reflections with I > 2σ(I). Crystal of BTPP is of monoclinic, space group P21/c with a = 11.6158(17), b = 11.2796(18), c = 13.082(2) ?, α = 90, β = 91.087(4), γ = 90o, V = 1713.7(5) ?3, Z = 4, Dc = 1.401 g/cm3, μ(MoKα) = 0.318 mm-1, Mr = 361.07, F(000) = 752, λ = 0.71070 ?, (?ρ)max = 0.322, (?ρ)min = –0.330 e/?3, the final R = 0.0563 and wR = 0.1058 for 3434 observed reflections with I > 2σ(I).
＜正＞In recent years, the utilization of multicomponent condensations （MCCs） to synthesize novel, drug-like scaf...
SHEN, Zhi-Liang JI, Shun-Jun (Key Labatoary of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineering, Suzhou University, Suzhou 215006)
＜正＞As an important class of pharmacologically active compounds, benzodiazepines are widely used in the last de...
GU, Da-Gong WANG, Hong-Xia JI, Shun-Jun Key Lab. of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineering of Suzhou University, Suzhou 215006
＜正＞Triazole derivates, thiadiazole and thiadiazine derivates are well known for their significant biological a...
ZENG, Xiao-Fei SHEN, Shu-Su LIU, Bin JI, Shun-Jun (Key Labarotary of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineering, Suzhou University, Suzhou 215006)
A one-pot synthesis of a series of 5-oxo-5,6,7,8-tetrahydro-4H-benzo-[b]-pyran derivatives via three-component coupling reactions of aldehydes, dimedone and malononitrilein room temperature ionic liquids （RTILs） without any catalyst has been reported. In the meantime, the reuse of ionic liquids and the effect of different ionic liquids as solvent on the reaction have also been investigated.
