A new method for the determination of arecoline in Semen Arecae decoction pieces by microchip capillary electrophoresis with contactless conductivity detection （MCE-CCD） was proposed. The effects of various electrophoretic operating parameters on the analysis of arecoline were studied. Under the optimal conditions, arecoline was rapidly separated and detected in 1 rain with good linearity over the concentration range of 20 1500 uM （r2=0.9991） and the detection limit of 5 uM （S/N=3）. The method was used for the analysis of arecoline satisfactorily with a recovery of 96.8 -104%.
A novel electromagnetic induction detector with two inductors for CE was described here.The two inductors were used as signal detection and reference,respectively.The parameters affecting the detector performance（including coil turns,detection distance, excitation frequency,voltage,etc.） were optimized.Under the optimum condition,the feasibility of the detector was examined by analyzing inorganic ions.The fabricated detector showed good linear relationship between the response and the analytes concentrations,with a detection limit of 13μmol/L for Na~＋（S/N = 3）.A variety of advantages,such as simple construction, ease of operation,and considerably universal response,suggested this novel detector a promising application prospect in analytical area.
