Three complexes of Mn（Ⅱ）with L-amino acid[L-Isoleucine（L-Ile）,L-Methionine（L-Met）,L-Tryptophan（L-Trp）]were synthesized and characterized by elemental analysis,infrared spectra and gravithem metrical analyses.The catalytic activity of the three complexes for disproportionation of O2-was determined by NBT method.The result shows that the complexes have a high SOD-like activity,and the KQ values of complexes 1,2 and 3 are 0.78×107mol-1·L·s-1,1.28×107mol-1,and 1.50×107mol-1L·s-1,respectively.
A dinuclear copper(Ⅱ) complex [Cu2(TATP)2(L-Leu)2(ClO4)2]2·2H2O was synthesized and characterized,where,TATP=1,4,8,9-tetraazatriphenylene,and L-Leu=L-leucinate. The complex was crystallized in the triclinic space group P1,with two independent molecules in a unit cell. Two Cu(Ⅱ) ions in each complex [Cu2(TATP)2(L-Leu)2(ClO4)2] molecule were found to be in different coordination geometries,i.e.,Cu2 or Cu4 of a distorted square-pyramidal geometry coordinated with two nitrogens of TATP,the amino nitrogen and one carboxylate oxygen of L-Leu and one oxygen of perchlorate,and Cu1 or Cu3 with an octahedral geometry coordinated with the above stated similar coordinated atoms,and another carboxylate oxygen of L-Leu coordinating to Cu2 or Cu4. The complex can interact with CT-DNA by an intercalative mode and cleave pBR322 DNA in the presence of ascorbate.
