研究了品红(FB)聚合膜修饰玻碳电极的制备及其电化学性质,并用于抗坏血酸(AA)的测定。在 pH7.0的磷酸盐缓冲溶液中,AA 在聚品红修饰玻碳电极上产生一灵敏的氧化峰,峰电流与 AA 的浓度在3.0×10^(-5)～8.7×10^(-3)mol/L 范围内呈良好的线性关系,检出限为 1.0×10^(-5)mol/L。该电极重现性良好,用于维生素 C 片中 AA 的测定,获得满意结果。
A novel capacitive sensor for pazufloxacin mesilate (pazufloxacin) determination was developed by electropolymerizing p-aminobenzene sulfonic (p-ABSA) and molecularly imprinted polymers (MIPs), which was synthesized through thermal radical copolymerization of metharylic acid (MAA) and ethyl-ene glycol dimethacrylate (EGDMA) in the presence of pazufloxacin template molecules, on the gold electrode surface. Furthermore, 1-dedecanethiol was used to insulate the modified electrode. Alter-nating current (ac) impedance experiments were carried out with a Model IM6e to obtain the capaci-tance responses. Under the optimum conditions, the sensor showed linear capacitance response to pazufloxacin in the range of 5 ng·mL-1 to 5 μg·mL-1 with a relative standard deviation (RSD) 5.3% (n=7) and a detection limit of 1.8 ng·mL-1. The recoveries for different concentration levels of pazufloxacin samples varied from 94.0% to 102.0%. Electrochemical experiments indicated the capacitive sensor exhibited good sensitivity and selectivity and showed excellent parameters of regeneration and stabil-ity.
