In practical multi-sensor information fusion systems, there exists uncertainty about the network structure, active state of sensors, and information itself (including fuzziness, randomness, incompleteness as well as roughness, etc). Hence it requires investigating the problem of uncertain information fusion. Robust learning algorithm which adapts to complex environment and the fuzzy inference algorithm which disposes fuzzy information are explored to solve the problem. Based on the fusion technology of neural networks and fuzzy inference algorithm, a multi-sensor uncertain information fusion system is modeled. Also RANFIS learning algorithm and fusing weight synthesized inference algorithm are developed from the ANFIS algorithm according to the concept of robust neural networks. This fusion system mainly consists of RANFIS confidence estimator, fusing weight synthesized inference knowledge base and weighted fusion section. The simulation result demonstrates that the proposed fusion model and algorithm have the capability of uncertain information fusion, thus is obviously advantageous compared with the conventional Kalman weighted fusion algorithm.